Titlebook: Metallomics; Recent Analytical Te Yasumitsu Ogra,Takafumi Hirata Book 2017 Springer Japan KK 2017 Metallomics.Speciation.Elemental imaging.

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Visualization of Intracellular Elements Using Scanning X-Ray Fluorescence Microscopyed plasma mass spectrometry, were developed previously. Applications allowing high-resolution imaging at the single-cell level are anticipated in cell biology and medicine, where the roles of elements, especially in relation to intracellular molecules such as proteins, nucleic acids, lipids, and sug

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Quantitative Elemental Bioimaging Protocol Using Femtosecond-Laser Ablation-ICP-Mass Spectrometry Corometry (fs-LA-ICP-MS). With the laser ablation under the finely controlled fluence, sliced alveolar tissue samples (thickness 1 μm), placed on the glass slide, were totally ablated, and the laser-induced sample aerosols were introduced into the ICP. Hence, no laser ablation was achieved on the glas

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77Se NMR Spectroscopy for Speciation Analysis of Selenium Compoundsis theoretically applicable to all metallic elements except cerium. In this chapter, we demonstrate selenium (Se) speciation in animal Se metabolites (selenometabolites) by NMR spectroscopy and review hitherto performed NMR spectroscopic studies of Se detection in biological samples. .Se, an NMR-act

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Protein Quantification and Quantitative Phosphorylation Analysis by the Determination of Hetero Atomion of proteins remains a major challenge in modern proteomics. Protein quantification was performed by the determination of sulfur (S) in trypsin-digested peptides by means of nanoHPLC-ICPMS under a flow of O. in an octopole reaction cell. Peptide concentrations were calculated as the ratio of the

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Analysis of Drug Active Pharmaceutical Ingredients and Biomolecules Using Triple Quadrupole ICP-MSpossible, making it highly suitable for the measurement of molecular compounds in life science research, including drug development. The tandem MS (MS/MS) configuration of the instrument, with a quadrupole positioned either side of the reaction cell, allows for much better control of any ion-molecul

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Highly Sensitive Analysis of Proteins and Metabolites by Metal Tagging Using LC-ICP-MSifferences in the amounts of proteins and metabolites in a biological sample, all of them must be considered for proteomics and metabolomics, even if their contents are very low. Now, the analytical technique with metal tag using liquid chromatography–inductively coupled plasma mass spectrometry (LC

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