| 书目名称 | Metallomics | | 副标题 | Recent Analytical Te | | 编辑 | Yasumitsu Ogra,Takafumi Hirata | | 视频video | | | 概述 | Provides basic and advanced analytical techniques and molecular biology for metallomics.Examines medical and pharmaceutical implications.Presents unique features of hybriding of elemental imaging and | | 图书封面 |  | | 描述 | This book focuses on recent topics in metallomics, a study of the metallome, or metal-containing biomolecules. Metals can induce various physiological and toxicological effects in a very small amounts, in other words, the concentrations of biometals are very low in organisms. Thus, analytical techniques for a trace amount of metal are crucial to understand the biological and toxicological functions of metals.This volume begins with an overview of metallomics including the history and development of the field. Subsequent parts provide basic and advanced techniques for metallomics. Speciation and imaging of metals are basic approaches to reveal the function of the metallome. The applications of speciation using an HPLC hyphenated with inductively coupled plasma mass spectrometry (LC-ICP-MS) and flow cytometry ICP-MS are described. As advanced approaches, the applications using a micro-flow injection-ICP-MS, an ICP-triple quadrupole mass spectrometer, an ICP-sector field mass spectrometer, and an ICP-multi-collector mass spectrometer are mentioned. For the imaging of metals, basic principles and applications of several techniques such as scanning X-ray fluorescence microscopy and ICP- | | 出版日期 | Book 2017 | | 关键词 | Metallomics; Speciation; Elemental imaging; Micro-XRF; NMR; Stable isotope; Trace elements; Metal transport | | 版次 | 1 | | doi | https://doi.org/10.1007/978-4-431-56463-8 | | isbn_softcover | 978-4-431-56793-6 | | isbn_ebook | 978-4-431-56463-8 | | copyright | Springer Japan KK 2017 |
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发表于 2025-3-21 18:12:05
