Titlebook: Meningococcal Vaccines; Methods and Protocol Andrew J. Pollard,Martin C.J. Maiden Book 2001 Springer Science+Business Media New York 2001 i

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Paul J. Brett,Ian M. Feavers,Bambos M. Charalambousen?..Wie werden Innovationsideen bewertet? ..Wie lange benötigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche Möglichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X

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Johan Holst,Bjørn Hanebergen?..Wie werden Innovationsideen bewertet? ..Wie lange benötigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche Möglichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X

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Andrew R. Gorringe,Karen M. Reddin,Pierre Voet,Jan T. Poolmanen?..Wie werden Innovationsideen bewertet? ..Wie lange benötigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche Möglichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X

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Carmen Arigita,Wim Jiskoot,Matthijs R. Graaf,Gideon F. A. Kersten

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Meningococcal Vaccines and Vaccine Developments,ve protection. This overview traces the development of the existing licensed vaccines and examines the prospects of vaccine candidates that are currently under development or subject to clinical evaluation.

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Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens D peptide or oligosaccharide that binds to the antibody in question and then determination of the structure of the bound antigen by X-ray crystallography. Clearly, this has the limitation that only well-defined continuous epitopes can be studied in this way, but fortunately this is frequently the cas

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Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetimultitude of different applications of biosensor technology including measurement of concentration, kinetic analysis, structural studies, fermentation monitoring, receptor-cell interactions, and equilibrium analysis. The most widespread applications have been to protein-protein interactions, in part

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Construction of porA Mutants,h experimental outer membrane-derived vaccines have shown that PorA is a major inducer of bactericidal antibodies (.–.), making it a crucial component of any meningococcal vaccine. These antibodies are highly subtype-specific. Epidemic strains tend to be clonal and mainly express a single PorA subty

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Construction of LPS Mutants,n several ways. First, the cell surface-exposed oligosaccharide part may contain epitopes recognized by bactericidal or otherwise protective antibodies; however, the presence of host-identical structures such as the terminal lacto-.-neotetraose means that the possibility of inducing autoimmune patho