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Titlebook: Meningococcal Vaccines; Methods and Protocol Andrew J. Pollard,Martin C.J. Maiden Book 2001 Springer Science+Business Media New York 2001 i

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书目名称Meningococcal Vaccines
副标题Methods and Protocol
编辑Andrew J. Pollard,Martin C.J. Maiden
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Medicine
图书封面Titlebook: Meningococcal Vaccines; Methods and Protocol Andrew J. Pollard,Martin C.J. Maiden Book 2001 Springer Science+Business Media New York 2001 i
描述Since the first recognition of outbreaks of cerebrospinal or spotted fever at the end of the nineteenth and the beginning of the twentieth centuries, the menace of the meningococcus has been high on the list of public health prio- ties. Few if any pathogens surpass the meningococcus in the rapidity and sev- ity with which it devastates previously healthy individuals. The challenge of understanding the biology of this fascinating microbe is immense, but few will doubt that successful control of meningococcal meningitis and septicemia will only transpire through the application of a body of extraordinary detailed inf- mation, including key minutiae of its molecular biology. In the first of two companion volumes, Meningococcal Vaccines, the team of experts gathered by Andy Pollard and Martin Maiden converge to p- vide an impressive accumulation of molecular tools with which to lay bare the secrets of the meningococcus. The results of this ambitious and welcome v- ume represent an exciting and much needed resource for all of us in the field.
出版日期Book 2001
关键词infectious diseases
版次1
doihttps://doi.org/10.1385/1592591485
isbn_softcover978-1-4899-4225-8
isbn_ebook978-1-59259-148-0Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightSpringer Science+Business Media New York 2001
The information of publication is updating

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978-1-4899-4225-8Springer Science+Business Media New York 2001
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Methods in Molecular Medicinehttp://image.papertrans.cn/m/image/630609.jpg
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Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity,Proteins with intrinsic mitogenic properties are widely represented in prokaryotes, such as in different . species (.–.), . (.), and . (.). Specifically, several bacterial porins of ., and pathogenic . species have been shown to induce nonspecific proliferation of lymphocytes (.–.).
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Early Experiences with Nasal Vaccines against Meningococcal Disease,In common with most infectious agents, meningococci invade mucosal membranes before causing disease (.). An attractive vaccine strategy is therefore to induce immunological responses at the mucosal surfaces, with the possibility of blocking microbial invasion, as well as to induce systemic immunity with the capacity of inactivating the microbes.
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