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Titlebook: Melanoma Development; Molecular Biology, G Anja Bosserhoff Book 20111st edition Springer-Verlag/Wien 2011 Melanoma.Senescence.Stem Cells.Tu

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Regulation of Apoptosis in Melanoma Cells: Targets for Therapeutic Strategies,resent suitable targets. Extrinsic (death receptor-mediated) and intrinsic (mitochondria-mediated) proapoptotic pathways have been described, and the better understanding how proapoptotic pathways are blocked in melanoma may provide a basis for the development of new therapeutic strategies.
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Introduction,me risk for developing melanoma in the US has increased from approximately 1 in 1,500 during the 1930s to its present risk of approximately 1 in 60 (Giblin and Thomas 2007). The American Cancer Society’s recent cancer report estimates that 68,130 new cases of melanoma will be diagnosed and 8,700 dea
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Melanoma Epidemiology,ffer by age and sex as well as geographic location. Light pigmentation and multiple nevi are critical risk factors for the development of melanoma as are family history and intermittent sun exposure. Tanning lamp exposure has been clearly identified as adverse risk for melanoma and other environment
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Altered Signal Transduction Pathways in Melanoma, and protein kinases, transcription factors, and other regulatory proteins. Naturally, this is the most important component in control of any cellular process, and therefore it is not surprising that it is often deregulated in cancer. Melanoma is in fact a paradigm for rewired signaling, since most
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