Titlebook: Mechanisms of Genome Protection and Repair; Dmitry O. Zharkov Book 2020 The Editor(s) (if applicable) and The Author(s), under exclusive l

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0065-2598 ory functions of bulky covalent modifications such as poly(ADP)ribosylation and ubiquitylation in DNA damage response, especially in the context of chromatin remodelling. As opposed to DNA repair, damage tolera978-3-030-41285-2978-3-030-41283-8Series ISSN 0065-2598 Series E-ISSN 2214-8019

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A Multifunctional Protein PolDIP2 in DNA Translesion Synthesis,ver PolDIP2 functions in DNA translesion synthesis and repair are not fully understood. In this review, we address the functional interaction of PolDIP2 with human DNA polymerases and discuss the possible functions in DNA damage response.

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0065-2598 gle proteins at an atomistic resolution to whole organisms.FDNA is under constant challenge from environmental and endogenous metabolic assaults. Several layers of defence and repair systems allow cells to maintain stable genomes; in humans, dysfunction of these systems leads to cancer, neurodegener

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Book 2020tain stable genomes; in humans, dysfunction of these systems leads to cancer, neurodegeneration, and other pathologies. At the same time, recently it had emerged that targeted and regulated DNA damage and repair is a mechanism underlying several important cellular processes such as epigenetic demeth

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Dmitry O. ZharkovDNA repair, the topic of this book, helps each human cell to survive millions of hits damaging its genome daily.Covers many levels, from single proteins at an atomistic resolution to whole organisms.F

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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/m/image/628724.jpg