Titlebook: Measles; Pathogenesis and Con Diane E. Griffin,Michael B. A. Oldstone Book 2009 The Editor(s) (if applicable) and The Author(s), under excl

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Ferrets as a Model for Morbillivirus Pathogenesis, Complications, and Vaccines,ipulation of viral genomes, the model has been used to evaluate the contribution of the accessory proteins C and V, and signalling lymphocyte activation molecule (SLAM)-binding to immunosuppression and overall pathogenesis. Similarly produced green fluorescent protein-expressing derivatives that mai

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Current Animal Models: Transgenic Animal Models for the Study of Measles Pathogenesis,e important in measles infection and in developing of new antiviral agentsand measles virus-based vaccines. In addition, as CD46 serves as a receptor for two other human viruses, some of these models may also find an important application in the study of adenovirus and herpesvirus 6 infection. In th

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Measles Studies in the Macaque Model,In addition, recent data are highlighted demonstrating that the application of a recombinant measles virus strain expressing enhanced green fluorescent protein dramatically increased the sensitivity of virus detection, both in living and sacrificed animals, allowing new approaches to old questions on measles vaccination and pathogenesis.

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Current Animal Models: Cotton Rat Animal Model,to investigate measles virus-induced immune suppression and suppression of vaccination by maternal antibodies. In addition, the cotton rat promises to be a useful model for the study of polymicrobial disease (interaction between measles virus and secondary pathogens).

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Measles Control and the Prospect of Eradication,ng population growth and demographic changes, conflict and political instability, and public perceptions of vaccine safety. To achieve the measles mortality reduction goal, continued progress needs to be made in delivering measles vaccines to the world‘s children.