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Titlebook: Measles; Pathogenesis and Con Diane E. Griffin,Michael B. A. Oldstone Book 2009 The Editor(s) (if applicable) and The Author(s), under excl

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Human Immunology of Measles Virus Infection,ompetent individuals, measles virus (MV) infection triggers an effective immune response that starts with innate responses and then leads to successful adaptive immunity, including cell-mediated immunity and humoral immunity. The virus is cleared and lifelong protection is acquired. However, changin
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Measles: Old Vaccines, New Vaccines,d vaccine provided only short-term protection and induced poor T cell responses and antibody that did not undergo affinity maturation. The response to this vaccine primed for atypical measles, a more severe form of measles, and was withdrawn. A live attenuated virus vaccine has been highly successfu
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Measles Virus for Cancer Therapy,or regressions have occurred during natural measles infections, but common tumors do not express SLAM, the wild-type MV receptor, and are therefore not susceptible to the virus. Serendipitously, attenuated vaccine strains of measles virus have adapted to use CD46, a regulator of complement activatio
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