Titlebook: MIF Family Cytokines in Innate Immunity and Homeostasis; Richard Bucala,Jürgen Bernhagen Book 2017 Springer International Publishing AG 20

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MIF Family Proteins in Cardiac Ischemia/Reperfusion Injury,ry still remains associated with the development of organ dysfunction and disconcerting complication rates, which results from myocardial ischemia/reperfusion injury and the perioperative inflammatory response. MIF is a structurally unique inflammatory cytokine with chemokine-like activities that ac

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MIF in Eosinophilic Inflammation,ic inflammation. Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine that not only contributes to the immune response to infection but also promotes tissue damage in sterile inflammation, and infectious conditions, is important in Th2 immune responses. Activated Th2 cells have i

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Parasite MIF Orthologs,ny of these have been investigated and reported upon. Crystallographic analyses have revealed close structural similarity of these with human MIF, and many of these parasite MIFs are able to bind directly to the human MIF receptor CD74. Additionally, most parasite MIFs demonstrate tautomerase activi

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Richard Bucala,Jürgen BernhagenProvides a comprehensive synthesis of the state-of-the-art of MIF science.Covers role of MIF in immunopathogenesis of different inflammatory, autoimmune, and infectious diseases.Provides outlook on MI

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978-3-319-84882-2Springer International Publishing AG 2017