书目名称 | MIF Family Cytokines in Innate Immunity and Homeostasis |
编辑 | Richard Bucala,Jürgen Bernhagen |
视频video | |
概述 | Provides a comprehensive synthesis of the state-of-the-art of MIF science.Covers role of MIF in immunopathogenesis of different inflammatory, autoimmune, and infectious diseases.Provides outlook on MI |
丛书名称 | Progress in Inflammation Research |
图书封面 |  |
描述 | The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress responses. MIF’s molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. New family members, such as D-dopachrome tautomerase, or MIF-2, and the closely homologous genes encoding by parasites have been defined and are being functionally characterized. MIF directed therapies also are entering clinical testing and ultimately may be applied in a pharmacogenomics manner. This book provides a comprehensive synthesis of the state-of-the-art of MIF science. The intended audience are post-graduate students and researchers in inflammation, innate immunity, immunology, and immunopathology. |
出版日期 | Book 2017 |
关键词 | Infectious Diseases; MIF Biology; MIF-directed therapies; MMIF; Macrophage Migration Inhibitory Factor ( |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-52354-5 |
isbn_softcover | 978-3-319-84882-2 |
isbn_ebook | 978-3-319-52354-5Series ISSN 1422-7746 Series E-ISSN 2296-4525 |
issn_series | 1422-7746 |
copyright | Springer International Publishing AG 2017 |