Titlebook: Lymphocyte Immunization Therapy (LIT) in Reproductive Failures; New Horizons Mohan Raut,Mugdha Raut Book 2022 Springer Nature Singapore Pte

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Introduction to Reproductive Immunology and Reproductive Failure protocols to a larger extent. This is more evident when these conditions are “unexplained.” As the role of alloimmune factor is significant in these conditions, unexplained RPL and unexplained RIF are considered together. This part discusses reproductive immunology and diagnosis of alloimmune facto

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Recurrent Pregnancy Loss and Recurrent Implantation Failure Failure. Nearly 50% of these patients are not aware of the cause of their pregnancy loss and so their cases are often referred to as “unexplained.” This chapter discusses the definitions, incidence, types, and classifications of RPL and RIF. It also talks about the importance of biochemical pregnan

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Immune Systemnes and chemokines) as well as organs within the immune system. The chapter discusses the normal immune response, types of immunity (innate and adaptive), the cells of the immune system, and the chemicals produced by them to induce the immune response. A brief explanation of the role played by Human

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History of LITwho first proposed that the maternal immune system has a big part to play in maintaining pregnancies that are immunologically different. The first LIT was used by Taylor and Faulk. However, it was Dr. Beer, who put forward the concept that failure of maternal recognition of paternal alloantigens cou

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Mechanism of Action of LITmunological mechanisms, like production of blocking antibodies and activation of Treg cells leading to decrease in Th17/Treg ratio. It also acts through activation of Th2 type of cytokines (anti-inflammatory) leading to a decrease in Th1/Th2 cytokine ratio. These changes are made possible by the rol

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