Titlebook: Lipids in Health and Disease; Peter J. Quinn,Xiaoyuan Wang Book 2008 Springer Science+Business Media B.V. 2008 Activation.Lipid.Metabolism

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Natasha C. Lucki,Marion B. Sewerterioration can be caused by a change in the composition of the sensing membrane. This is of particular importance in the case of liquid membranes [1] since their components exhibit high mobilities, therefore rather low molecular weights and, hence, usually moderate lipophilicities. All these proper

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Transcriptional Regulation of Hepatic Fatty Acid Metabolismism of fatty acids. Two transcription factors, namely SREBP1-c and PPARα, appear to be the main players controlling synthesis and degradation of fatty acids respectively. This chapter briefly presents fatty acid metabolism. The first part focuses on SREBP1-c contribution to the control of gene expre

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Fatty Acid Amide Hydrolase: A Gate-Keeper of the Endocannabinoid Systemerol (2-AG). These compounds are the main endogenous agonists of cannabinoid receptors, able to mimic several pharmacological effects of Δ.-tetrahydrocannabinol (Δ.-THC), the active principle of . preparations like hashish and marijuana. The activity of AEA at its receptors is limited by cellular up

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Modulation of Inflammatory Cytokines by Omega-3 Fatty Acidsyunsaturated fatty acids (omega-6 and omega-3 fatty acids) are the precursors of the lipid mediators and play an important role in regulation of inflammation. Generally, omega-6 fatty acids (e.g. arachidonic acid) promote inflammation whereas omega-3 fatty acids (e.g. eicosapentaenoic acid and docos

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Eicosanoids in Tumor Progression and Metastasislogical responses. These bioactive metabolites are part of complex cascades that initiate and perpetuate several disease processes such as atherosclerosis, arthritis, neurodegenerative conditions, and cancer. The intricate role played by each of these metabolites in the initiation, progression, and