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Titlebook: Lipids in Health and Disease; Peter J. Quinn,Xiaoyuan Wang Book 2008 Springer Science+Business Media B.V. 2008 Activation.Lipid.Metabolism

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发表于 2025-3-21 17:35:09 | 显示全部楼层 |阅读模式
书目名称Lipids in Health and Disease
编辑Peter J. Quinn,Xiaoyuan Wang
视频video
概述The lipids represent targets for cell regulation.Their role in signaling processes increasingly recognized.Their role in cell-cell recognition and social behaviour of cells is identified.Potential the
丛书名称Subcellular Biochemistry
图书封面Titlebook: Lipids in Health and Disease;  Peter J. Quinn,Xiaoyuan Wang Book 2008 Springer Science+Business Media B.V. 2008 Activation.Lipid.Metabolism
描述Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsa
出版日期Book 2008
关键词Activation; Lipid; Metabolism; Oxidation; enzymes; regulation; transcription
版次1
doihttps://doi.org/10.1007/978-1-4020-8831-5
isbn_softcover978-90-481-8001-1
isbn_ebook978-1-4020-8831-5Series ISSN 0306-0225 Series E-ISSN 2542-8810
issn_series 0306-0225
copyrightSpringer Science+Business Media B.V. 2008
The information of publication is updating

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发表于 2025-3-21 23:56:46 | 显示全部楼层
Transcriptional Regulation of Hepatic Fatty Acid Metabolismmarizing recent advances in our current understanding of how these two transcription factors fit in the regulatory networks that sense hormones or nutrients, including cellular fatty acids, and govern the transcription of genes implicated in hepatic fatty acid metabolism.
发表于 2025-3-22 00:24:37 | 显示全部楼层
Signalling Pathways Controlling Fatty Acid Desaturationid desaturases gene transcription. Here, we review recently discovered components and mechanisms of the regulatory machinery governing the transcription of fatty acid desaturases in bacteria, yeast and animals.
发表于 2025-3-22 07:38:54 | 显示全部楼层
Fatty Acid Synthase Activity in Tumor Cellst also in developing inhibitors that target FASN specifically as an anti-tumor modality. Pharmacological blockade of FASN activity has identified a pleiotropic role for FASN in mediating aspects of proliferation, growth and survival. As a result, a clearer understanding of the role of FASN in tumor cells has been developed.
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Eicosanoids in Tumor Progression and Metastasismetastasis of solid tumors has been a subject of intense research in the scientific community. This review summarizes some of the key aspects of eicasonoids and the associated enzymes, and the pathways they mediate in promoting tumor progression and metastasis.
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Phospholipid-Mediated Signaling and Heart Diseases review provides an outline of the role of phospholipase A., C and D and subsequent signal transduction mechanisms in different cardiac pathologies with a discussion of their potential as targets for drug development for the prevention/treatment of heart disease.
发表于 2025-3-23 08:34:47 | 显示全部楼层
https://doi.org/10.1007/978-1-4020-8831-5Activation; Lipid; Metabolism; Oxidation; enzymes; regulation; transcription
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