| 书目名称 | Lipid Hydroperoxide-Derived Modification of Biomolecules |
| 编辑 | Yoji Kato |
| 视频video | |
| 概述 | Provides novel aspects of the nature of lipid hydroperoxides.Wide range information from chemistry to pathology related to lipid hydroperoxide.Includes methodology of oxidative stress biomarker analys |
| 丛书名称 | Subcellular Biochemistry |
| 图书封面 |  |
| 描述 | Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is formed in an initial step of lipid peroxidation. Lipid hydroperoxide is also known as a potential source of singlet oxygen. Harmful aldehydes are formed when the lipid hydroperoxide is degraded. The formed aldehyde has high reactivity against thiol or amine moieties. Therefore, it could act as a signaling molecule, which might induce the changing of gears inside a cell. Recent studies have shown that lipid hydroperoxide or a slightly modified product of the lipid hydroperoxide reacts with biomolecules such as proteins and aminophospholipids, which leads to formation of amide-type adducts. Amide-type adducts could be one of markers for oxidative stress and could also be an important player in some diseases. In this book, the chemistry and biochemistry of lipid hydroperoxide along with their conjugates with biomolecules are described. |
| 出版日期 | Book 2014 |
| 关键词 | covalent adducts; lipid hydroperoxide; oxidative stress; singlet oxygen |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-7920-4 |
| isbn_softcover | 978-94-024-0296-4 |
| isbn_ebook | 978-94-007-7920-4Series ISSN 0306-0225 Series E-ISSN 2542-8810 |
| issn_series | 0306-0225 |
| copyright | Springer Science+Business Media Dordrecht 2014 |
发表于 2025-3-21 16:50:02
