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Titlebook: Leukemia Stem Cells in Hematologic Malignancies; Haojian Zhang,Shaoguang Li Book 2019 The Editor(s) (if applicable) and The Author(s), und

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发表于 2025-3-21 18:26:53 | 显示全部楼层 |阅读模式
书目名称Leukemia Stem Cells in Hematologic Malignancies
编辑Haojian Zhang,Shaoguang Li
视频video
概述Introduces readers to the biology of leukemia stem cells.Emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies.Covers the molecular signatures of leu
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Leukemia Stem Cells in Hematologic Malignancies;  Haojian Zhang,Shaoguang Li Book 2019 The Editor(s) (if applicable) and The Author(s), und
描述.This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc..
出版日期Book 2019
关键词leukemia stem cells; blood cancer; targeted therapy; drug resistance; disease relapse
版次1
doihttps://doi.org/10.1007/978-981-13-7342-8
isbn_softcover978-981-13-7344-2
isbn_ebook978-981-13-7342-8Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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发表于 2025-3-21 20:49:50 | 显示全部楼层
RNA ,,-Methyladenosine Modification in Normal and Malignant Hematopoiesis,matopoietic stem cells, tissue development, circadian rhythm, heat shock or DNA damage response, and sex determination. Thus, it is not surprising that dysregulation of the m.A machinery is also closely associated with pathogenesis and drug response of both solid tumors and hematologic malignancies.
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DNA Damage Response in Quiescent Hematopoietic Stem Cells and Leukemia Stem Cells,, the DDR of LSCs were summarized based on the major outcomes triggered by different pathways in specific leukemia, upon which some aspects for future investigations were envisioned under our currently limited scope of knowledge.
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发表于 2025-3-22 13:27:47 | 显示全部楼层
Lindsay M. Gurska,Kristina Ames,Kira Gritsmane is a widespread problem across all fields of applied science. .Intelligent Tinkering. offers an insightful look at the underlying causes of the problem, along with invaluable suggestions for addressing it..978-1-61091-040-8Series ISSN 2945-5391 Series E-ISSN 2945-5405
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Hengyou Weng,Huilin Huang,Jianjun Chene is a widespread problem across all fields of applied science. .Intelligent Tinkering. offers an insightful look at the underlying causes of the problem, along with invaluable suggestions for addressing it..978-1-61091-040-8Series ISSN 2945-5391 Series E-ISSN 2945-5405
发表于 2025-3-23 07:16:38 | 显示全部楼层
Kanak Joshi,Lei Zhang,Peter Breslin S.J.,Jiwang Zhange is a widespread problem across all fields of applied science. .Intelligent Tinkering. offers an insightful look at the underlying causes of the problem, along with invaluable suggestions for addressing it..978-1-61091-040-8Series ISSN 2945-5391 Series E-ISSN 2945-5405
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