| 书目名称 | Isolation and Molecular Characterization of Circulating Tumor Cells |
| 编辑 | Mark Jesus M. Magbanua,John W. Park |
| 视频video | |
| 概述 | Informative and authoritative, this book presents state-of-the-art strategies for CTC research from experts and key opinion leaders in the field.This book contains creative and innovative ideas for ra |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities. Despite this clinical significance, the molecular biology of CTCs remains poorly understood. The paucity in molecular information can be attributed to the tremendous technical challenges involved in isolating these extremely rare cells. Recent technological advancements in rare-cell technology, however, have allowed for the reliable enrichment and isolation of CTCs. Consequently, the use of recently developed molecular approaches —e.g., multiplexed QPCR, microarray, and next generation sequencing analyses— to profile CTCs have provided novel insights into the molecular makeup of these tumor cells. This book discusses approaches for enrichment and isolation of CTCs as well as recent advances in comprehensive molecular profiling of CTCs using cutting-edge omics technology. |
| 出版日期 | Book 2017 |
| 关键词 | Circulating tumor cells; Rare-cell technology; Expression profiling; Genomic DNA profiling; Clinical app |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-55947-6 |
| isbn_softcover | 978-3-319-85787-9 |
| isbn_ebook | 978-3-319-55947-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 18:56:31
