Titlebook: Ion Mobility-Mass Spectrometry; Methods and Protocol Giuseppe Paglia,Giuseppe Astarita Book 2020 Springer Science+Business Media, LLC, part

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Drift-Tube Ion Mobility-Mass Spectrometry for Nontargeted ′Omicsyses. Harnessing the additional, orthogonal separation that DTIM provides increased confidence in compound identifications as the mass spectral complexity can be reduced and mobility-derived parameters (most prominently the collision cross section, .) used to support identity confirmation goals for

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The Use of DMS-MS for the Quantitative Analysis of Acylcarnitines reduces chemical background and enhances signal-to-noise (S/N) ratio. Flow injection analysis (FIA) is a technique used to introduce samples into the source of the DMS-MS platform. Here we describe the application of FIA-DMS-MS/MS for the analysis of urinary acylcarnitine species. More than 20 acyl

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Traveling Wave Ion Mobility-Mass Spectrometry to Enhance the Detection of Low Abundance Features in on their size and conformation. Over the last years, it was demonstrated that the comparative analysis of ion mobility data has the potential to highlight the presence of low abundance species in untargeted lipidomics. The present chapter illustrates the background of the topic and guides the reade

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A Workflow for the Identification of Mycotoxin Metabolites Using Liquid Chromatography–Ion Mobility-f the large number of isomeric forms. Here, we describe the use of ion mobility-mass spectrometry to analyze cereal extracts and how structural information on newly discovered mycotoxins metabolites could be obtained.

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Quantitation of Cyclosporin A in Cell Culture Media by Differential Mobility Mass Spectrometry (DMS-entration of pharmaceutical in a medium such as Hank’s Balanced Salt Solution with HEPES organic buffer (HBSS-HEPES) is measured at a series of time points, making simplicity and high throughput of the analytical method important characteristics. We report an electrospray differential mobility spect

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