Titlebook: Ion Channels as Targets in Drug Discovery; Gary Stephens,Edward Stevens Book 2024 The Editor(s) (if applicable) and The Author(s), under e

obstinate

MODE

Validation of TMEM16A Modulation as a Therapeutic Approach for the Treatment of Cystic Fibrosis: Thdeliver benefit. In this chapter we describe the discovery of a novel tool compound (ET002663), which effectively potentiates the activity of TMEM16A, and the studies undertaken to validate the concept of enhancing TMEM16A activity as a novel approach for the treatment of cystic fibrosis.

hankering

SOW

小卷发

Voltage-Gated Sodium Channels as Drug Targets in Epilepsy-Related Sodium Channelopathies,targeting VGSCs in the treatment of epilepsy-related sodium (Na) channelopathies. Notwithstanding significant technical hurdles, modulators of VGSCs are likely to remain a mainstay in the treatment of epilepsy-related channelopathies and epilepsy more generally.

小教堂

Therapeutic Targeting of Potassium Channels,onsequently, K. channels are validated drug targets for many of these disorders. The aim of the present chapter is to provide an overview of the therapeutic targeting of K. channels, paying attention to new developments in the field.

FILTH

Phonophobia

辫子带来帮助

渗透