| 书目名称 | Insights into Receptor Function and New Drug Development Targets |
| 编辑 | Michael Conn,Claude Kordon,Yves Christen |
| 视频video | |
| 概述 | Includes supplementary material: |
| 丛书名称 | Research and Perspectives in Endocrine Interactions |
| 图书封面 |  |
| 描述 | .We are now on the verge of viewing effector molecules and other regulatory sites as therapeutic targets for the amelioration of human and animal disease. The recognition, for example, that mutant proteins are frequently misrouted molecules, rather than functionally defective ones, changes our approach to "inborn errors of metabolism" and offers new approaches for pharmacological discovery, based on rescue of receptors, ion channels and enzymes with pharmacoperones. Ion channels, regulators of G-protein signaling and enzymes engaged in regulation, now present opportunities for drug development...The state of our art also benefits by the availability of superior tools that allow measurement of interactions and afford unprecedented insight into the biomolecular interactions that present novel approaches to drug design.. |
| 出版日期 | Conference proceedings 2006 |
| 关键词 | Cannabinoid; G protein-coupled receptors; G proteins; RGS proteins; TRPC channels; endogenous cannabinoid |
| 版次 | 1 |
| doi | https://doi.org/10.1007/3-540-34447-0 |
| isbn_softcover | 978-3-642-07080-8 |
| isbn_ebook | 978-3-540-34447-6Series ISSN 1861-2253 Series E-ISSN 1863-0685 |
| issn_series | 1861-2253 |
| copyright | Springer-Verlag Berlin Heidelberg 2006 |
发表于 2025-3-21 18:50:53
