Titlebook: Inhibition of Folate Metabolism in Chemotherapy; The Origins and Uses George H. Hitchings Book 1983 Springer-Verlag Berlin Heidelberg 1983

东西

PAD416

DEMUR

Musket

Dihydrofolate Reductasencreasingly well-documented concept of “the unity of biochemistry” which emphasized the commonality of pathways employed by both prokaryotes and eukaryotes for their growth and reproduction (F. 1974).

glucagon

Selective Inhibitors of Bacterial Dihydrofolate Reductase: Structure-Activity Relationships higher water solubility. Other competitors have masked trimethoprim (TMP) in the form of various prodrugs, or in the form of various soluble or insoluble salts, in an effort to modify its pharmacokinetic properties. This type of modification will not be discussed in this chapter, because of the difficulty of evaluating proprietary claims.

promote

Adverse Effects of Co-trimoxazolee it is not possible using this technique to assess retrospectively the validity of most published studies of adverse reactions. Nevertheless it is to be hoped that approaches such as advocated by this group will be adopted in the future, so as to render interpretation of case reports of adverse reactions a much easier task.

cluster

破译

Trimethoprim/Sulfamethoxazole: An Overviewfonamides in 1932 (see D. 1935). After widespread and effective use of sulfonamides in a variety of infectious diseases, resistant organisms began to emerge, at first slowly, but then with frightening rapidity. In Japan, for example, species of . were invariably sensitive to sulfonamides in the mid

厨师

infringe