Titlebook: Inclusion Bodies; Methods and Protocol Julian Kopp,Oliver Spadiut Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusiv

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Andreas Schwaighofer,Bernhard Lendlitha practical interest in questions relating to the complete vehicle. The formula material is prepared in such a way that the book can also be used as a reference work... ..978-3-658-39669-5978-3-658-39667-1

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Intensification of Inclusion Body Processing via Temperature-Based Refolding

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Inclusion Bodies: Status Quo and Perspectives,discuss the state-of-the art biopharmaceutical IB process, review its challenges, highlight the recent developments and perspectives, and also propose alternative solutions, compared to the state-of-the art processing.

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Inclusion Body Production in Fed-Batch and Continuous Cultivation Thus, the interest in establishing continuous cultivations, facilitating higher space-time yields, has been increased in recent years. In this protocol, we provide information and a guide to set-up the production of recombinant proteins in fed-batch, as well as in chemostat continuous cultivations using ..

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High Pressure Homogenization for Inclusion Body Isolationnted in combination with analytical methods suitable to evaluate these unit operations. The protocol is based on a multivariate approach to identify suitable conditions during HPH. Furthermore, the described workflow is easily scalable and can, therefore, also be used if fixed homogenization conditions are already established.