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Titlebook: Implications of the Blood-Brain Barrier and Its Manipulation; Volume 1 Basic Scien Edward A. Neuwelt Book 1989 Plenum Publishing Corporatio

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Pharmacology of the Blood-Brain Barrier,trast, the standard methods of measuring the permeability coefficient cannot be employed for the cerebral capillaries, since neither the capillary surface area nor the composition of the blood within the capillaries and the interstitial fluid surrounding them can be tightly controlled or precisely k
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Drug Delivery to the Brain by Blood-Brain Barrier Circumvention and Drug Modification,ossibly less extreme but of equal importance is the clinical observation that CNS drug-delivery problems are prevalent in the treatment of patients with acute cerebral bacterial and viral infections as well as with neurotransmitter and enzyme-deficiency diseases, such as Parkinson, Huntington, and T
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Book 1989ciplines applied from a view­ point of integrative physiology rather than from only molecular or analytical approaches. It is this broad scope that is emphasized in this book. In my opinion, four original contributions define the field as it exists today. The first, a monograph by Broman,1 entitled
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