Titlebook: Implication of Oxysterols and Phytosterols in Aging and Human Diseases; Gérard Lizard Book 2024 The Editor(s) (if applicable) and The Auth

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The Structure of Oxysterols Determines Their Behavior at Phase Boundaries: Implications for Model Meir arrangement at the phase boundary, and interactions with other lipids and proteins. As a result, physicochemical properties of biomembranes (i.e., elasticity, permeability, and ability to bind proteins) are modified, which in turn may affect their functioning. The observed effect depends on the t

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Chemical and Biochemical Features of Spinasterol and Schottenolhrene nucleus composed of 3 hexane rings and of a pentane ring with an alkyl side chain. There are around more than 250 phytosterols and related compounds that have been identified in natural resources. Among them, spinasterol and schottenol, its dihydro analog, are often found in seeds, and consequ

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Oxysterols in Central and Peripheral Synaptic Communicationty, a substantial portion of synaptic cholesterol can be oxidized by either enzymatic or non-enzymatic pathways to form oxysterols, which in turn modulate the activities of neurotransmitter receptors (e.g., NMDA and adrenergic receptors), signaling molecules (nitric oxide synthases, protein kinase C

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Oxysterols in Infectious Diseasesxysterols and their receptors in bacterial and viral infections of the respiratory and gastrointestinal tracts. Oxysterols are produced in response to infections and have multiple roles including chemotaxis of immune cells to the site of infection and regulation of inflammation. Some oxysterols have

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Impact of Oxysterols in Age-Related Disorders and Strategies to Alleviate Adverse Effectsnzymatic and non-enzymatic processes. They are widely reported in animal-origin foods and prove significant involvement in the regulation of cholesterol homeostasis, lipid transport, cellular signaling, and other physiological processes. Reports of oxysterol-mediated cytotoxicity are in abundance an

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