Titlebook: Impacts of Medications on Male Fertility; Erma Z. Drobnis,Ajay K. Nangia Book 2017 Springer International Publishing AG 2017 Male fertilit

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Challenges of Obtaining Evidence-Based Information Regarding Medications and Male Fertility,ation to evidence-based practice. In this chapter, we discuss the limitations of the current literature and the challenges to designing more useful studies. Among the most important weaknesses of existing studies is lack of power; that is, too few men are included to draw conclusions about the exist

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Pain Medications and Male Reproduction, well known, but this topic is absent from the current conversations about these medications. In the fertility clinic, a significant proportion of our patients are using opioids for pain management, and the options for these men are unclear. Opioids exert their negative effects by a variety of mecha

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,5α-Reductase Inhibitors (5ARIs) and Male Reproduction,tment reduces male hair loss. These drugs inhibit the conversion of testosterone to the more active dihydrotestosterone (DHT). In men taking these medications, DHT levels are reduced by some 90% while testosterone levels remain relatively stable. Well known for their negative effects on libido and e

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Cardiovascular/Pulmonary Medications and Male Reproduction,hese drugs have been associated with sexual dysfunction, including erectile and ejaculatory dysfunction, but for most there is insufficient evidence to link their use with testicular dysfunction, reduced semen quality or infertility. Some exceptions are the irreversible α.-adrenergic antagonist phen

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Antivirals and Male Reproduction,r. HIV has become a chronic disease, and many men with HIV desire children. The disease itself has profound negative effects on semen quality, as does infection with hepatitis C virus (HCV), so treatment with antivirals generally improves semen quality in men with longer duration of infection and/or