书目名称 | Immunotherapy for Head and Neck Cancer |
编辑 | Anthony T. C. Chan,Brigette B.Y. Ma |
视频video | |
概述 | Crosses disciplines to provide peer reviewed chapters on a multi-disciplinary theme.Updates the field by comprehensively covering head and neck cancers.Presents novel therapeutics for immunotherapy in |
丛书名称 | Cancer Immunotherapy |
图书封面 |  |
描述 | This book is a comprehensive summary of the literature on the scientific rationale and clinical development of immunotherapy for head and neck cancers..Head and neck cancer is a biologically diverse group of cancers that bear a common hallmark - evasion of host immune surveillance through innate or acquired mechanisms. The etiological association between the Human Papilloma virus (HPV) and some squamous head and neck cancers, the Epstein-Barr virus (EBV) and nasopharyngeal cancer has provided further impetus for evaluating immunotherapy in this group of cancers. The successful development of anti-programmed cell death protein-1 (PD-1)/ ligand (PD-L1) and CTLA-4 antibodies in solid tumours has gradually brought immunotherapy into mainstream oncological practice in recent years. Besides immune-checkpoint proteins inhibitors, other forms of immunotherapy such as vaccines, EBV or HPV-targeting therapies and cellular therapies are actively being investigated in clinical trials, either alone or in combination with other conventional treatments such as radiotherapy, chemotherapy and surgery. In clinical setting, the practicing oncologist need to be familiar with some unusual patterns of i |
出版日期 | Book 2023 |
关键词 | Nasopharyngeal Cancer; Combinatorial approaches of immunotherapy and cytotoxic therapy; Immunotherapy; |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-031-29223-1 |
isbn_softcover | 978-3-031-29225-5 |
isbn_ebook | 978-3-031-29223-1Series ISSN 2662-8384 Series E-ISSN 2662-8392 |
issn_series | 2662-8384 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |