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Titlebook: Immunotherapy for Head and Neck Cancer; Anthony T. C. Chan,Brigette B.Y. Ma Book 2023 The Editor(s) (if applicable) and The Author(s), und

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Drug Targets and Strategies in the Clinical Development of Immunotherapy for Head and Neck Cancer,election should mainly be based on the PD-L1 expression combined positive score, patient symptoms, the need for rapid tumor shrinkage, possible autoimmune comorbidities, and contraindications to chemotherapies. While PD-1 inhibitors have shown impressive long-term responses in some R/M SCCHN patient
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Clinical Application of Immunotherapy in the Perioperative Management of Head and Neck Cancer,ral studies of perioperative ICI monotherapy suggest that programmed cell death 1 receptor ligand (PD-L1) expression enriches for benefit from immunotherapy. Although early data is promising, not all patients respond to immunotherapy, and further work is ongoing to identify predictive biomarkers, ad
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Development of Predictive Biomarkers to Immunotherapy in Head and Neck Cancer,n that may help optimizing response to immunotherapeutic strategies. In addition, an integration of multiple biomarkers at multiple time points may be required to successfully optimize predictive power for immunotherapy response.
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covery. Raisman and Field [7], using the electron microscope, demonstrated that elimination of one input to the septal nucleus is substituted by new synapses which were formed by the sprouting of the remaining fibers in the rat. Tsukahara et al. [9], using an intracellular recording technique, demon
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