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Titlebook: Immunosenescence; Graham Pawelec Book 2007 Springer-Verlag New York 2007 Immunosenescence.age.aging.assessment.autoimmune disease.cancer.i

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发表于 2025-3-21 18:41:47 | 显示全部楼层 |阅读模式
书目名称Immunosenescence
编辑Graham Pawelec
视频video
丛书名称Medical Intelligence Unit
图书封面Titlebook: Immunosenescence;  Graham Pawelec Book 2007 Springer-Verlag New York 2007 Immunosenescence.age.aging.assessment.autoimmune disease.cancer.i
描述.Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disease plateaus at around 80 years of age in industrialised countries, but death due to infectious disease continues to increase up to 100 years of age and beyond. Understanding the reasons for age-associated alterations to protective immunity in the elderly would facilitate the development of interventions to reconstitute appropriate immune function, increase responsiveness to vaccination and extend healthspan. The majority of the papers collected in this volume therefore address not only the mechanisms responsible for immune ageing in humans but consider what might be accomplished to redress the erosion of immune competence with age..
出版日期Book 2007
关键词Immunosenescence; age; aging; assessment; autoimmune disease; cancer; infectious diseases; morbidity; senesc
版次1
doihttps://doi.org/10.1007/978-0-387-76842-7
isbn_softcover978-1-4419-2639-5
isbn_ebook978-0-387-76842-7
copyrightSpringer-Verlag New York 2007
The information of publication is updating

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书目名称Immunosenescence读者反馈学科排名




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Scoring of Immunological Vigor: Trial Assessment of Immunological Status as a Whole for Elderly Peodeveloping countries. Nonetheless, infections such as pneumonia and urinary tract infection rank 4th and 5th even in Japan. These data are mainly based on death certificates from medical doctors without autopsy. However, infection is found to be a major cause of death in the elderly where autopsy is
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Remodelling of the CD8 T-Cell Compartment in the Elderly: Expression of NK Associated Receptors on only on chronological ageing itself, but also on exogenous factors such as persistent antigenic stress leading to chronic activation of the immune system. The most significant changes occur in the T-cell compartment, with decreasing naïve cells and increasing numbers of cells with a memory/activated
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T-Cell Signalling, a Complex Process for T-Cell Activation Compromised with Aging: When Membrane Ra as well as adaptive, undergo immunosenescence. However, the adaptive immune response and especially T-cells are the most affected by aging. Aging is associated with both changes in lymphocytes subpopulations and, importantly, functional changes within these subsets. Indeed, T-cells present function
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The Efficacy of Vaccines to Prevent Infectious Diseases in the Elderly,cted by infectious diseases and they display distinct features with respect to clinical presentation and treatment. Although vaccinations are considered a vital medical procedure for preventing morbidity and mortality caused by infectious diseases, the protective effect of vaccinations is abrogated
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Zinc and the Altered Immune System in the Elderly,. The decline of immune function with aging, so-called immunosenescence, has several parallels with immunological alterations observed during zinc deficiency; thus, it is plausible that both events are associated, implying an impact of altered zinc status on immune function in the elderly. This is s
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