Titlebook: Immobilization of Enzymes and Cells; Methods and Protocol Jose M. Guisan,Juan M. Bolivar,Javier Rocha-Martín Book 2020Latest edition Spring

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Jose M. Guisan,Fernando López-Gallego,Juan M. Bolivar,Javier Rocha-Martín,Gloria Fernandez-Lorenteal technical challenges. For example, excess wild-type (WT) DNA often masks low-level DNA alterations containing clinically relevant information for cancer diagnosis or therapy. In this chapter, we describe nuclease-assisted minor allele enrichment with probe overlap (NaME-PrO), an approach to reduc

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Alessandra Basso,Simona Serbannt blood samples sequentially over time and thereby serve as surrogates to assess the biology of surviving cancer cells that may still persist in solitary or multiple metastatic sites following treatment. CTCs may thus function as potential real-time decision-making guides for selecting appropriate

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Jose M. Guisan,Fernando López-Gallego,Juan M. Bolivar,Javier Rocha-Martín,Gloria Fernandez-Lorentes. Human blood and other body fluids represent rich sources for the identification of novel biomarkers. It is apparent that the availability of these biomarkers would improve an early detection of asymptomatic disease and the clinical management of cancer. MicroRNAs have been described to be present

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Fernando López-Gallego,Gloria Fernandez-Lorente,Javier Rocha-Martín,Juan M. Bolivar,Cesar Mateo,Jose, their number has steadily grown to approximately 2500 known microRNAs at present in humans. MicroRNAs encoded by distinct genes regulate the expression of about 30–60 % of human protein coding genes by targeting their messenger RNAs (mRNAs) and induce mostly posttranscriptional inhibition, or in s

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Cesar Mateo,Benevides C. C. Pessela,Manuel Fuentes,Rodrigo Torres,Claudia Ortiz,Fernando López-Galleight be, but is prevented by his past. An economy of trade sets the limit to the kind of lives they can lead; it does not make them what they are. It does not supply an identity. Indeed, what interests us about them is their . energy: their excess, their drivenness. We might perhaps say that the eco

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Gloria Fernandez-Lorente,Javier Rocha-Martín,Jose M. Guisan either side of the High Street, and boards placed on the trestles to form two long counters. At seven o’clock, the market bell rings: ‘it would surprise a stranger to see in how few minutes, without hurry or noise, and not the least disorder, the whole market is filled’. The clothiers have been wai

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