| 书目名称 | Images of Biologically Active Structures in the Immune System |
| 副标题 | Their Use in Biology |
| 编辑 | Hilary Koprowski (Director),Fritz Melchers |
| 视频video | http://file.papertrans.cn/462/461583/461583.mp4 |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | The diversity of antigen-binding structures of antibody molecules is so vast that every conceivable antigen can be bound by an antibody molecule within the immune system. This is true even for the antigen binding sites of antibodies called idiotypes, which are bound by complementary bind ing sites of other antibodies called anti-idiotypes. Thus, anti-idiotypes are structural homologues of antigens. These idiotypic-anti-idiotypic interactions constitute a network within the immune system. Since one lymphocyte produces only one type of antibody molecule, this network is in fact a network of cells. We expect that the network is functional: the appearance of antigen will disturb the equilibrium of the network at the point where it competes with the anti idiotypic lymphocyte for binding to the idiotypic lympho cyte. It has been known for quite some time that anti idiotypic antibody can be used to prime the immune system for memory to an antigen that it has never seen. This phe nomenon is now being explored for possible use in immuni zation against viruses, bacteria, parasites and tumors as well as for the modulation of autoimmunity. The ability of anti-idiotypes to mimic, both ant |
| 出版日期 | Book 1985 |
| 关键词 | Antigen; Structures; System; antibody; autoimmunity; bacteria; immune system; parasite; virus |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-70675-2 |
| isbn_softcover | 978-3-642-70677-6 |
| isbn_ebook | 978-3-642-70675-2Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
|Archiver|手机版|小黑屋|
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