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Titlebook: Identifying Hidden Needs; Creating Breakthroug Keith Goffin,Fred Lemke,Ursula Koners Book 2010 Palgrave Macmillan, a division of Macmillan

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Keith Goffin BSc (DUNELM), MSc, PhD,Fred Lemke BCom (HONS), MBA, PhD,Ursula Koners BA (HONS), DIPLOMto acquire essentially all fragment ion spectra in a single LC-ESI-MS/MS experiment. Since the direct correlation between a precursor and its fragment ions is lost when acquiring all ions in a defined ./. range, one data analysis strategy is using so-called peptide spectral libraries. These are usua
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in the central nervous system (CNS). In this sense, mass spectrometry (MS) methods have proven to be sensitive in quantifying the proteomic profiles of CSF, therefore being able to detect biomarker candidates for neurological disorders. In particular, a key development has been the use of multiplex
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