Titlebook: Hypoxia and the Circulation; Robert C. Roach (Research Director),Peter D. Wagne Conference proceedings 2007 The Editor(s) (if applicable)

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GenetiC Mechanisms Underlying Regulation of Hemoglobin Mass,izing machinery and with limited energy metabolism. While a number of genetic mechanisms can result in decreased hemoglobin concentration in the blood, this review concentrates on those that lead to increased hemoglobin mass, i.e. polycythemia or erythrocytosis. Polycythemia may be due to a) mutatio

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Control of the Respiratory Pattern in Insects,tinguished by the presence of an open phase in which the spiracular valves are fully open, a closed phase during which oxygen concentrations at the tissues are lowered, thereby reducing oxidative damage, and a flutter phase in which the spiracles open intermittently for very brief periods,. The flut

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Effects of Insect Body Size on Tracheal Structure and Function,eologic estimates suggest that atmospheric oxygen in the late Paleozoic Era was 35%. These findings have led to a prominent hypothesis that insect body size may be limited by oxygen delivery. Empirical evidence from developing . grasshopper experiments suggests that larger/older animals are not more

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The Role of Hif-1 1 in Hypoxic Response in the Skeletal Muscle,ve its function through that stress is central to its role in the body. The primary transcriptional response factor for hypoxic adaptation is hypoxia inducible factor-1α (HIF- 1α), which upregulates glycolysis and angiogenesis in response to low levels of tissue oxygenation. To examine the role of H

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Gene Expression in Working Skeletal Muscle,functional consequences of the exercise-induced changes in gene expression. Muscle cells are able to detect mechanical, metabolic, neuronal and hormonal signals which are transduced over multiple pathways to the muscle genome. Exercise activates many signaling cascades - the individual characteristi

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0065-2598 omedicine. Hypoxia is a constant threat to the human body and its vital organs throughout life. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. ..The International Hypoxia Symposia was founded to enable

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