Titlebook: Hyperglycemia, Diabetes and Vascular Disease; Neil Ruderman,Joseph Williamson,Michael Brownlee Book 1992 American Physiological Society 19

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Book 1992crovas­ cular pathology in the retina and glomerulus and they are at a 2--6-fold greater risk for atherosclerotic vascular disease than individuals without diabetes. In addition, hypertension is far more prevalent in patients with diabetes than in the general population. As a consequence of these co

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Cerebral Microvascular Transport and Metabolism: Implications for Diabetes result, descriptive in vivo studies of physiology can now be extended, and precise molecular mechanisms underlying transport changes can be determined Recent studies also extend basic knowledge of how diabetes affects microvascular function and metabolism in the brain.

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Cell Culture Model for the Study of Vascular Complications of Diabetes: The Effect of High Glucose LVascular complications affect all diabetic patients to some extent and involve both microvessels and macrovessels. In this chapter we discuss studies that show the effects of elevated glucose levels on the metabolism of retinal and aortic vascular cells in culture.

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https://doi.org/10.1007/978-1-4614-7524-8Diabetes; Diabetes mellitus; Hyperglycemia; Vascular Disease; endothelium; metabolism; physiology; signal t

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Neil Ruderman,Joseph Williamson,Michael BrownleeThere are over 12 million people with diabetes in the US.The authors review clinical, epidemiological, and biochemical evidence that high levels of blood glucose produce metabolic and biochemical alte

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