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Titlebook: Human Neural Stem Cells; From Generation to D Leonora Buzanska Book 2018 Springer International Publishing AG, part of Springer Nature 2018

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发表于 2025-3-21 18:11:15 | 显示全部楼层 |阅读模式
书目名称Human Neural Stem Cells
副标题From Generation to D
编辑Leonora Buzanska
视频video
概述Summarizes the most recent advances in human neural stem cells (hNSC) research.Presents hNSC derivation methods.Discusses mechanisms underlying NSC in vitro fate decisions and their in vivo therapeuti
丛书名称Results and Problems in Cell Differentiation
图书封面Titlebook: Human Neural Stem Cells; From Generation to D Leonora Buzanska Book 2018 Springer International Publishing AG, part of Springer Nature 2018
描述.This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic mode of action..The long-standing dogma that the human central nervous system (CNS) lacks the ability to regenerate was refuted at the end of the 20th century, when evidence of the presence of neurogenic zones in the adult human brain was found. These neurogenic zones are home to human neural stem cells (hNSCs), which are capable of self-renewing and differentiating into neurons, astrocytes and oligodendrocytes. NSCs isolated from human CNS have a number of clinical advantages, especially the innate potential to differentiate into functional neural cells. Nevertheless, their full clinical exploitation has been hindered by limited access to the tissue and low expansion poten
出版日期Book 2018
关键词human neural stem cells; hNSC; hNSC derivation; hNSC differentiation; hNSC engineering; hNSC clinical app
版次1
doihttps://doi.org/10.1007/978-3-319-93485-3
isbn_softcover978-3-030-06671-0
isbn_ebook978-3-319-93485-3Series ISSN 0080-1844 Series E-ISSN 1861-0412
issn_series 0080-1844
copyrightSpringer International Publishing AG, part of Springer Nature 2018
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