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Titlebook: Human Apolipoprotein Mutants 2; From Gene Structure C. R. Sirtori,G. Franceschini,G. Assmann Book 1989 Springer Science+Business Media New

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Human Apolipoprotein A-I: Studies on Gene Expression and Site-Directed Mutagenesis in ,dies indicate that exogenous administration of HDL-like apolipoproteins might result in positive effects on various experimental models (Stein et al., 1979; Koizumi et al., 1986). However, the difficulty to obtain pure apo A-I from human plasma in sufficient amounts has severely limited the explorat
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Apolipoprotein AI-Milano: Mechanisms for the Antiatherogenic Potentialor arginine substitution at the position 173 in the primary sequence of apo AI (3), leading to the formation of disulphide bonded homodimers AI-M/AI-M and heterodimers with apolipoprotein AII (AI-M/AII) (2).
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Apolipoprotein-Specific High Density Lipoprotein Populations in Plasma of Carriers of the Apolipoproarticle size profile that consists primarily of two major peaks, one in the HDL. size interval (8.8–8.2 nm) and the other in the HDL. size interval (8.2–7.8 nm); and (iii) their unique protein moiety that includes the apoAI. variant, identified by an Arg 173 → Cys substitution (1,2). While the prese
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Apo B Gene Variants are Involved in Determining Serum Cholesterol Levels: Towards Identifying these a better definition of these factors. In the case of cholesterol, for example, we know from a number of studies that 50% of the total phenotypic variance in the population is due to environmental factors and 50% due to genetic factors, with variation at a number of genetic loci contributing to this
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Genetic Evidence that the Apolipoprotein Gene is not Involved in Abetalipoproteinemiaesis in the liver and intestine are important to our understanding the development of hyperlipidaemia and atherosclerosis. It may be possible to obtain a better idea of the control of apo B synthesis by studying patients with defects in the synthesis and secretion of apo B containing lipoproteins.
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