Titlebook: Histone Recognition; Ming-Ming Zhou Book 2015 Springer International Publishing Switzerland 2015 Chromatin.Control of gene expression.Epig

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Methylarginine Recognition by Tudor Domains, methyllysine- and methylarginine-binding subtypes, with close to ten Tudor domain-containing proteins in each subtype. In this chapter, we will highlight the biological roles of the Tudor domains that interact with arginine-methylated peptide motifs.

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Muffle

黑豹

savage

Book 2015o therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner..

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Activating Latent HIV by Inhibiting Bromodomain Proteins,ularly at the transcription phase. Here, we provide a review of HIV latency and transcription, of the emergent role of bromodomain-containing proteins in HIV biology, and of studies with chemical inhibitors of bromodomains to activate HIV from latency.

Mortal

音乐会

Will be of interest to researchers and graduate students in .This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinat

雪白

The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription,of epigenetic regulation that is currently under investigation by numerous researchers. In this chapter, we take a closer look at the structure and functions of the BrD, as well as its interaction with other chromatin-associated modules and its overall role in disease biology.