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Titlebook: Histone Recognition; Ming-Ming Zhou Book 2015 Springer International Publishing Switzerland 2015 Chromatin.Control of gene expression.Epig

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发表于 2025-3-21 17:25:31 | 显示全部楼层 |阅读模式
书目名称Histone Recognition
编辑Ming-Ming Zhou
视频videohttp://file.papertrans.cn/428/427292/427292.mp4
概述Enriches our understanding of the complex regulation of gene expression.Written by leading scientists who made the key original discoveries.Will be of interest to researchers and graduate students in
图书封面Titlebook: Histone Recognition;  Ming-Ming Zhou Book 2015 Springer International Publishing Switzerland 2015 Chromatin.Control of gene expression.Epig
描述.This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner..
出版日期Book 2015
关键词Chromatin; Control of gene expression; Epigenetics; Gene transcription; Histone recognition; Site-specifi
版次1
doihttps://doi.org/10.1007/978-3-319-18102-8
isbn_softcover978-3-319-37666-0
isbn_ebook978-3-319-18102-8
copyrightSpringer International Publishing Switzerland 2015
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Histone Recognition by WD40 Proteins,e range of recognition modes that have been described. Specifically, the binding of RbAp46/48 proteins to histones H4 and H3, WDR5 recognition of the histone H3 tail and EED sensing of the histone H3K27 methylation state, will be discussed.
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Histone Recognition by Tandem Modules and Modulation by Multiple PTMs,tion by multiple PTMs from a structural perspective with implications on biological outcome. The molecular recognition events discussed here illustrate how chromatin regulators make use of paired or integrated “reader” modules to translate particular histone PTM signatures into specific biological o
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Chao Xu,Gaofeng Cui,Maria Victoria Botuyan,Georges Merating to type in the field, and occupy different microhabitats on the same shore. Therefore, laboratory-based experiments were performed to determine if assortative mating was maintained in sympatry and also to determine the effect of population density on mate choice. The males of both populations
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Robert E. Collins,Xiaodong Chengnegal offering a different set of challenges for management and promotion. Additionally, while the first group of sites are relatively accessible and attracted a significant number of tourists prior to the designation, the stone circles are less accessible and receive fewer visitors. This chapter as
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Alexsandra Espejo,Mark T. Bedfordct no: TR51/15/DFD/0015] was funded by Ankara Regional Development Agency of Ministry of Development in 2015. Project coordinator is Governor of Polatlı District; project partners are Museum of Anatolian Civilisations, Ministry of Culture and Tourism, Gordion Excavation Team, Mersin University and P
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