Titlebook: Histone Deacetylases; Methods and Protocol Sibaji Sarkar Book 2016 Springer Science+Business Media New York 2016 epigenetics.deacetylation

预测

Biomarker

面包屑

prosperity

Expression and Function of Histone Deacetylase 10 (HDAC10) in B Cell Malignancieslted in a rapid induction of cell death in vitro with only 5 % of cells being alive at 48 h, cell cycle arrest, and up-regulation of co-stimulatory molecules. Here we present several standard methods to study the function of HDAC10 in B cell malignancies.

离开就切除

Sibaji SarkarIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts

洞察力

ethereal

https://doi.org/10.1007/978-1-4939-3667-0epigenetics; deacetylation of histones in the nucleus; deacetylation of cytoplasmic signaling proteins

肿块

Analysis of Histone Deacetylase 7 (HDAC7) Alternative Splicing and Its Role in Embryonic Stem Cell D (ES) cell differentiation. Alternative splicing gives rise to vast diversity over gene information, arousing public concerns in the last decade. In this chapter, we describe a strategy to detect HDAC7 alternative splicing and analyze its function on ES cell differentiation.

Irksome

Cloning and Characterization of Sirtuin3 (SIRT3)ation of various metabolic and antioxidant enzymes, in turn controlling energy metabolism, stress resistance, and the pace of ageing. To study the function of SIRT3, a proteomics-based approach is employed for identifying the protein-binding partners of this enzyme in mitochondria.

thrombosis

978-1-4939-8111-3Springer Science+Business Media New York 2016