Titlebook: Hematologic Malignancies; Case Studies in Cyto Manorama Bhargava Book 2021 Springer Nature Singapore Pte Ltd. 2021 Case studies in Hematolo

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Multiple Myelomas, translocations involving MYC and somatic mutations affecting MAP K (KRAS, NRAS, BRAF, TRAF3, CYCD, LTB, and DNA repair pathways (TP53, ATM, ATR). Double-hit myelomas have any two high-risk factors and triple-hit myelomas any three high-risk factors..The following case studies on multiple myeloma demonstrate these alterations (Annexure).

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Book 2021nic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail.  The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if r

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etation. The resulting technique (abstract diagnosis) leads to elegant bottom-up and top-down verification methods, which do not require to determine the symptoms in advance, and which are effective in the case of abstract properties described by finite domains.

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Manorama Bhargavae problems and which type of improvements we can suggest. In a second part, we give an overview of some industrial CHIP applications, where the visualisation tools led to significant improvements in the applications. At the end, we present an analysis of the existing tools and some directions for further improvements.

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