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Titlebook: Hematologic Malignancies; Case Studies in Cyto Manorama Bhargava Book 2021 Springer Nature Singapore Pte Ltd. 2021 Case studies in Hematolo

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书目名称Hematologic Malignancies
副标题Case Studies in Cyto
编辑Manorama Bhargava
视频videohttp://file.papertrans.cn/426/425548/425548.mp4
概述Explains the significance of the results obtained towards the prognosis and treatment response.Presents several case studies in hematologic malignancies with particular reference to cytogenetics.Descr
图书封面Titlebook: Hematologic Malignancies; Case Studies in Cyto Manorama Bhargava Book 2021 Springer Nature Singapore Pte Ltd. 2021 Case studies in Hematolo
描述.This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail.  The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book
出版日期Book 2021
关键词Case studies in Hematology; Case studies in Cytogenetics; Case studies in molecular hematology; Cytogen
版次1
doihttps://doi.org/10.1007/978-981-33-4799-1
isbn_softcover978-981-33-4801-1
isbn_ebook978-981-33-4799-1
copyrightSpringer Nature Singapore Pte Ltd. 2021
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Manorama Bhargavasome kind of tree and the diagnosis amounts to search for a kind of . in this tree. Several search strategies are possible. The principles of an implementation are described, with a diagnosis session.
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ormation retrieval. By making comparisons between time periods, the historical development of research fields can be studied, and knowledge organization systems (e.g., thesauri) can be updated. These are concerns of citation network analysis (Borgman and Furner, 2002).
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Manorama Bhargavae subsequent analyses are based on these citing authors’ collective view of the intellectual relationships in their scholarly community or research field as recorded in the reference lists of their publications.
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Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) seen in a high proportion of cases, most common being SRSF2, TET2, and or ASXL1 in more than 80% cases. Co-mutation of SRSF2 and TET2 is highly specific for patients with CMML..The following case studies include cases of atypical CML, BCR-ABL1 negative, and CMML with detailed cytogenetic features (Annexure).
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