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Titlebook: Haplotyping; Methods and Protocol Brock A. Peters,Radoje Drmanac Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive

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书目名称Haplotyping
副标题Methods and Protocol
编辑Brock A. Peters,Radoje Drmanac
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Haplotyping; Methods and Protocol Brock A. Peters,Radoje Drmanac Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive
描述.This book aims to be an introduction to haplotype information for both the wet and dry labs. Chapters detail co-barcoding and linked-reads based methods, third generation sequencing based methods, Hi-C based methods, single-cell and Strand-seq, and methods for using haplotype data once obtained. Written in the successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.. ..Authoritative and cutting-edge, .Haplotyping: Methods and Protocols .aims to provide compréhensive and accessible methods to undergraduate, graduate, and established scientists..
出版日期Book 2023
关键词PCR; Bead emulsion; Chromosomal Phasing; stcLFR; mRNA sequencing
版次1
doihttps://doi.org/10.1007/978-1-0716-2819-5
isbn_softcover978-1-0716-2821-8
isbn_ebook978-1-0716-2819-5Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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Haplotyping978-1-0716-2819-5Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Methods in Molecular Biologyhttp://image.papertrans.cn/h/image/424089.jpg
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Read-Based Phasing and Analysis of Phased Variants with WhatsHap,ably long) reads covering at least two heterozygous variants. It offers additional tools for working with phased variant calls such as computing statistics, comparing different phasings and assigning reads in alignment files to their haplotype.
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Determining Complete Chromosomal Haplotypes by mLinker,that the complete chromosomal haplotype of diploid human genomes can be determined using molecular linkage from Hi-C sequencing and linked-reads sequencing [.]. In this chapter, we present a step-by-step guide to perform this analysis using mLinker, a software package for haplotype inference.
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