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Titlebook: Handbook of Anticancer Pharmacokinetics and Pharmacodynamics; Michelle A. Rudek,Cindy H. Chau,Howard L. McLeod Book 2014Latest edition Spr

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楼主: malcontented
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Pharmacodynamic Modeling, study design optimized not only for the determination of clinical response and toxicity, but also for optimal measure of pharmacokinetic and pharmacodynamic measures. Pharmacodynamic models, study design, and pharmacodynamic biomarkers for anti-cancer clinical trials are discussed.
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,Verilog – A Tutorial Introduction,s a major role in the NER-pathway because of its damage recognition and excision ability. This chapter will review mechanisms of DNA repair and platinum resistance as it relates to the NER pathway and regulation of ERCC1. A brief discussion on the role of cancer stem cells in platinum resistance is also presented.
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DNA Repair: ERCC1, Nucleotide Excision Repair, and Platinum Resistance,s a major role in the NER-pathway because of its damage recognition and excision ability. This chapter will review mechanisms of DNA repair and platinum resistance as it relates to the NER pathway and regulation of ERCC1. A brief discussion on the role of cancer stem cells in platinum resistance is also presented.
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Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/h/image/420812.jpg
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https://doi.org/10.1007/978-1-4614-9135-4Cancer; Pharmacodynamics; Pharmacogenetics; Pharmacokinetics; Pharmacology
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