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楼主: Grant
发表于 2025-3-25 05:09:50 | 显示全部楼层
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Biosynthesis and Biological Role of Insulin-like Growth Factors in the Nervous System ensuring the optimal development of the CNS and its later function. In recent years it has become increasingly evident that these processes are regulated by the complex interaction of several growth factors, such as fibroblast growth factor (FGF), nerve growth factor (NGF) and the insulin-like grow
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Growth Hormone Treatment of Children with Intrauterine Growth Retardationerform clinical trials in a large variety of patients who are growing poorly. A growth response to treatment with GH has been obtained in children with short stature and normal growth hormone secretion, the most prominent example being the treatment of children with Turner syndrome (Rosenfeld et al.
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Adel Moustafa,Ahmed G. Fahmy,Rim S. Hamdyto study GH action is further motivated by the fact that several cell lines lose their GH receptors under in vitro conditions. For example, the liver is a major GH responsive tissue where GH receptors are abundant; however, in many hepatoma cell lines we have studied the receptor levels are low. Thi
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Bulent Armagan,Nurettin Besli,Deniz Ucaracterization has also shown that numerous post-translational modifications of these proteins can occur. Specifically IGFBP-1 through 5 have been shown to be proteolytically cleaved. These proteases exist in a variety of physiologic fluids and therefore are capable of modifying binding protein activi
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