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楼主: indulge
发表于 2025-3-26 23:58:34 | 显示全部楼层
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https://doi.org/10.1007/978-94-007-0683-5(1–4). Unusual in the realm of drug design, they are peptides that have been invented prior to the discovery of the endogenous peptide hormone. In fact after more than 13 years of study, the putative GHRP-like hormone and its receptor have yet to be isolated. Further, GHRPs act in fundamentally diff
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Angeline Cyriac,Toji Thomas,T. Dennis Thomasomatotropin release inhibiting factor (SRIF) (Scheme 11.1). The factor controlling the episodic nature of GH release is unknown but its effects are probably mediated by feedback loops involving the positive effector GHRH and the negative regulator SRIF (1). In 1984, Bowers and Momany and coworkers (
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A. E. Osbourn,J. P. Wubben,M. J. Danielsd somatostatin. Areas of the hypothalamus responsible for the control of GH release are the somatostatin neuron-containing periventricular nucleus (PeV) (1–3) and the GHRH neuron-containing arcuate nucleus (4–6).
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Beitrag zur Cytologie von Melandriumt peptide (7, 8) and nonpeptidyl GH secretagogues (9, 10). Since these secretagogues are active in man and synergize strongly with GHRF (11–13), they could prove clinically valuable to release GH in patients that respond poorly to GHRF (14).
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