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发表于 2025-3-23 12:41:23 | 显示全部楼层
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Growth Hormone Binding Proteinshe existence of bound forms of circulating Polypeptide hormones has given way to over 430 publications dealing with various aspects of the GHBP, as listed in Medline at the time of this writing. Space limitations for this chapter do not permit citation of all; I apologize to those colleagues whose w
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The Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPS)s bound to a “carrier protein” increasing its apparent molecular weight from 7.5kDa to between 50 and 150kDa (Zapf et al 1975). It wasn’t until 1989 that this carrier protein was analysed in detail and shown to comprise the predominant serum binding protein, now termed IGFBP-3 and an ∼85kDa, acid la
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The Diagnosis of Adult Growth Hormone Deficiencyosition, physical fitness, and psychological well-being (Jorgensen .., 1989; Salomon .., 1989). The evidence has been sufficiently convincing that replacement therapy for adults with GH deficiency has been approved for this indication in several countries. Accurate diagnosis of GH deficiency is impo
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