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Titlebook: Glycoscience: Biology and Medicine; Tamao Endo,Peter H. Seeberger,Naoyuki Taniguchi Living reference work 20200th edition

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Carl Claus,Karl Grobben,Alfred Kühncan subtype found in most cells and tissues on a wide range of proteins with diverse functions. Mucin family molecules are among the best studied .-GalNAc glycoproteins, possessing hundreds of .-glycosylation sites in repeated domains rich in Ser/Thr; hence .-GalNAc glycans are also called mucin-typ
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Lehrbuch der allgemeinen Geophysiksyl-tryptophan. C-Mannosylation usually occurs at the first Trp in the consensus amino acid sequence Trp-x-x-Trp (W-x-x-W) in proteins through an enzymatic reaction with a specific mannosyltransferase. Recently, . DPY-19 was identified as a C-mannosyltransferase. Most substrates for C-mannosylation
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Lehrbuch der angewandten FluidmechanikC) or circulatory half-time in vivo. Although the attached .-glycans are mostly core α1-6-fucosylated biantennary glycans, minor nonhuman .-glycans having .-glycolylneuraminic acid (NeuGc) and Galα1-3Gal epitopes (αGal) have been reported to be present in therapeutic mAbs. Determination of nonhuman
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Darstellende Geometrie der Flächenkrümmungaride functions in many biological events. In order to elucidate oligosaccharide functions, glycoproteins having homogeneous oligosaccharides that can be varied as much as chemists like are requisite. Chemical synthesis of glycoproteins recently emerged and provides homogeneous glycoproteins such as
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Lehrbuch der darstellenden Geometrie α-sialylation of various acceptors in non-coordinating solvents such as CH.Cl.. The protection is also effective for improving the reactivity of the hydroxy group at the eight position. In addition, protecting groups of the alcohol in exocyclic side chain affected not only their reactivity towards
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Lehrbuch der darstellenden Geometrieintriguing targets of therapeutic intervention. Metabolic oligosaccharide engineering has been employed to install azides on .’s glycans. Azide-bearing glycoproteins were then covalently elaborated via Staudinger ligation with a variety of phosphine probes to facilitate detection, identification, an
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