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Titlebook: Glycoscience: Biology and Medicine; Tamao Endo,Peter H. Seeberger,Naoyuki Taniguchi Living reference work 20200th edition

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楼主: Jaundice
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Biological Functions of C1GalT1 and Mucin-Type ,-Glycans,can subtype found in most cells and tissues on a wide range of proteins with diverse functions. Mucin family molecules are among the best studied .-GalNAc glycoproteins, possessing hundreds of .-glycosylation sites in repeated domains rich in Ser/Thr; hence .-GalNAc glycans are also called mucin-typ
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C-Mannosylation: A Modification on Tryptophan in Cellular Proteins,syl-tryptophan. C-Mannosylation usually occurs at the first Trp in the consensus amino acid sequence Trp-x-x-Trp (W-x-x-W) in proteins through an enzymatic reaction with a specific mannosyltransferase. Recently, . DPY-19 was identified as a C-mannosyltransferase. Most substrates for C-mannosylation
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Carbohydrate-Based Gamete Recognition During the Sperm Acrosome Reaction in Sea Urchins,s for penetrating the extracellular matrix of the egg, binding to the egg surface, and fusing with the egg plasma membrane, has been a central issue in research into sperm–egg interactions. Unambiguously, sea urchin spermatozoa trigger the AR upon contact with the thick gelatinous layer (egg jelly)
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Chemical Synthesis of Oligosialic Acid by Using 5-,,4-,-Carbonyl-Protected Sialyl Donors, α-sialylation of various acceptors in non-coordinating solvents such as CH.Cl.. The protection is also effective for improving the reactivity of the hydroxy group at the eight position. In addition, protecting groups of the alcohol in exocyclic side chain affected not only their reactivity towards
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,Chemical Tools to Detect and Target ,’s Glycoproteins,intriguing targets of therapeutic intervention. Metabolic oligosaccharide engineering has been employed to install azides on .’s glycans. Azide-bearing glycoproteins were then covalently elaborated via Staudinger ligation with a variety of phosphine probes to facilitate detection, identification, an
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