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Titlebook: Glycoprotein Methods and Protocols; The Mucins Anthony P. Corfield Book 2000 Humana Press 2000

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Kurvendarstellung im rechtwinkligen Netz novel mucins present during purification from mucus, to quantitation of specific mucin core proteins or carbohydrate moieties present in clinical samples. This chapter discusses procedures and limitations of several different strategies available to detect and quantify these glycoproteins from biol
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https://doi.org/10.1007/978-3-662-29957-9complex glycoproteins (.,.). These secretory mucins form mucous layers on the apical side of the cells, protecting the vulnerable epithelium, while allowing selective interactions with the apical environments, which is typically the lumen of an organ that is continuous with the outer world. Secretio
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https://doi.org/10.1007/978-3-662-29955-5orming mucins. These molecules share the ability to assemble into long oligomeric structures via the agency of disulfide bonds. There is evidence that at least four mucins—MUC2, MUC5AC, MUC5B, and MUC6 (.–.)—are gel-forming mucins, and it is possible that there are others. In isolating a mixture of
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,Die Erkrankungen des äußeren Ohres,urfaces from damaging effects and agents (..,.). Mucous gels are not pure mucin but contain other components secreted into the gel, e.g., IgA and protein, lipid, and nucleic acid from shed epithelial cells, and particularly, in the lower GI tract from bacteria. When measuring the rheological propert
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Aliphatische Schwefelverbindungen,tion), it is challenging to assign the sites of glycosylation (macroheterogeneity) and the carbohydrate heterogeneity at a given glycosylation site (microheterogeneity). Typically, the characterization of macro- and microheterogeneity has been dependent on the isolation of small peptides with only o
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https://doi.org/10.1007/978-3-642-69232-1ancer research. Mucins, which are constituents of mucus, have a lubricating and protective function in normal epithelial tissue (.). However, expression of mucin by the cancer cell is often highly disorganized and upregulated, sometimes to the extent that mucin can be detected in the circulation of
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