Titlebook: Gigaseal Formation in Patch Clamping; With Applications of Majid Malboubi,Kyle Jiang Book 2014 The Editor(s) (if applicable) and The Author

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https://doi.org/10.1007/978-3-642-39128-6Gigaseal Formation using micropipettes; High Resistance Seals; High throughput screening; Hydrophilicit

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Development of Patch Clamping,gy and medicine. The technique not only allowed the detection of single-channel currents in biological membranes for the first time but also enabled higher current resolution, direct membrane patch potential control, and physical isolation of membrane patches [2]. The development of the patch clamp method was honoured with a Nobel Prize in 1991.

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2191-530X hly desirable at both research and industrial levels. Nanotechnology has been found to be a powerful tool for studying and modifying glass micropipettes and in tackling the problem of gigaseal formation..978-3-642-39127-9978-3-642-39128-6Series ISSN 2191-530X Series E-ISSN 2191-5318

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Book 2014their latest methods for achieving gigaseal formation and describe techniques that are highly desirable at both research and industrial levels. Nanotechnology has been found to be a powerful tool for studying and modifying glass micropipettes and in tackling the problem of gigaseal formation..

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