Titlebook: Genomics, Proteomics, and Clinical Bacteriology; Methods and Reviews Neil Woodford,Alan P. Johnson Book 2004 Humana Press 2004

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Discovering New Pathogens a new perspective to the study of polymicrobial infections such as gingivitis, and offers the potential for the detection and identification of novel bacterial pathogens from among complex and numerous endogenous microbial flora.

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Exploring the Concept of Clonality in Bacteriarial pathogens are very diverse, whereas others are genetically uniform, and some are, in essence, a single clone of a mother species that has been raised to species status due to the distinctiveness of the disease it causes (e.g., ., or .). The population structures of bacteria depend on the rate o

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Bacterial Taxonomicsl-subunit ribosomal RNA genes (rDNA) leading to the construction of branching trees representing the distance of divergence from a common ancestor has provided the mainstay of microbial phylogenetics. The approach has some limitations, particularly in the discrimination of closely related taxa, and

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1064-3745 o fruition. The advances in genomics and proteomics have already given us frequent opportunities to reassess our knowledge and understanding of established b- terial adversaries, and have provi978-1-61737-428-9978-1-59259-763-5Series ISSN 1064-3745 Series E-ISSN 1940-6029

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https://doi.org/10.1007/978-3-663-13568-5ies, as well as in national reference laboratories. Presently, molecular biology offers a wide repertoire of techniques and permutations. This chapter is intended to explore the application of these in the diagnostic laboratory setting.