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Titlebook: Genomic Instability and Immortality in Cancer; Enrico Mihich,Leland Hartwell Book 1997 Springer Science+Business Media New York 1997 DNA.M

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https://doi.org/10.1007/978-1-4939-1607-8a tumor suppressor gene,. pRb, binds to some members of the E2F family, including E2F-1, and transforms them into transcriptional repressors.. In this manner, pRb performs at least part its growth suppressive function.
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https://doi.org/10.1007/978-3-662-62692-4, evolutionary conserved proteins (Biessman and Mason, 1992). For example, both . and yeast telomeres have heterochromatic properties and share the ability of modulating the expression of adjacent genes, a phenomenon called telomere position effect (Levis et al., 1985; Shore, 1995).
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https://doi.org/10.1007/978-3-642-96136-6o maintain genomic integrity. By studying how the yeast cell controls the fidelity of the genome we hope to further our understanding of those cellular functions that work coordinately to ensure genomic integrity.
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Telomeres and Cell Division in ,,, evolutionary conserved proteins (Biessman and Mason, 1992). For example, both . and yeast telomeres have heterochromatic properties and share the ability of modulating the expression of adjacent genes, a phenomenon called telomere position effect (Levis et al., 1985; Shore, 1995).
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W. Mombour,G. Kockott,R. Degkwitz In a variety of organisms, these telomeric repeat arrays are known to be maintained by telomerase, a ribonucleoprotein reverse transcriptase that synthesizes single strand copies of the unit telomeric repeat onto the 3’ end of the chromosomal terminus by using part of its RNA subunit as a template (Blackburn, 1994; Zakian, 1995).
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